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lipL [2019-05-08 12:43:56]
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lipL [2019-05-08 12:43:56]

GcvH
locus
BSU37640
pI
5.27
mw
31.27 kDa
protein length
281 aa Sequence Blast
gene length
846 bp Sequence Blast
function
lipoic acid metabolism
product
GcvH
essential
no
ec
2.3.1.204
synonyms
ipa-90d,ywfL
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.7|Biosynthesis and scavenging of lipoic acid]

    • Gene

    Coordinates
    3,863,415 → 3,864,260

    The protein

    Protein family

  • Octanoyltransferase LipL family (according to UniProt)

    • Structure

  • [PDB|2P5I] (from ''Bacillus halodurans'', 56% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|F2E881F4BE0968C75BD75A5EFF4C7CA642034796|lipL]
    description
    [Pubmed|9353933]
    view in new tab

    Biological materials

    Mutant

  • MGNA-B667 (ywfL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1666 NBRP B. subtilis, Japan]
  • BKE37640 (Δ[gene|F2E881F4BE0968C75BD75A5EFF4C7CA642034796|lipL]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE37640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTATGTAAAACCCTTTC, downstream forward: _UP4_TGAACGTTCTTCGCATGCCG
  • BKK37640 (Δ[gene|F2E881F4BE0968C75BD75A5EFF4C7CA642034796|lipL]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK37640 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTATGTAAAACCCTTTC, downstream forward: _UP4_TGAACGTTCTTCGCATGCCG

    • References

    Reviews

  • 27074917

    • Original publications

  • 9353933,21338420,21338421